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nsc-87877

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  • Inhibitors & Agonists
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NSC-87877
T1635056990-57-9
NSC-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (IC50=0.318 μM, 0.355 μM of shp2 and shp1, respectively).It also inhibits dual-specificity phosphatase 26 (DUSP26).
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NSC-87877 disodium
NSC87877
T691156932-43-5
NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1 2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability proliferation.
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