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(1)
By Target- Autophagy
- HDAC(1)
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By Target By ResearchField- Cancer(1)
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Results for "
nsc-726630
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- Rac-BelinostatPXD101, PX-105684, NSC726630T1852414864-00-9Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
- $37
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- Belinostat
PXD-101, PXD101, PX105684T8517866323-14-0Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.- $40
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