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(2)
By Target- Apoptosis
- Autophagy(2)
- DNA Alkylator/Crosslinker(2)
- DNA/RNA Synthesis(1)
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By Target By ResearchField- Cancer(1)
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Results for "
nsc-362856
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Isotope Products1
- TemozolomideTZM, TMZ, NSC 362856, CCRG 81045T117885622-93-1Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.
- $42
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Cited - Temozolomide-D3TMID-1105208107-14-6Temozolomide-D3 is the deuterated form of Temozolomide. Temozolomide (T1178) (NSC 362856) is an orally active DNA alkylating agent capable of crossing the blood-brain barrier. It also acts as an autophagy inducer and an apoptosis agent. This compound is effective against tumor cells characterized by low levels of O6-alkylguanine-DNA alkyltransferase (OGAT) and dysfunctional mismatch repair systems. Temozolomide (T1178) exhibits anti-tumor and anti-angiogenic effects.
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