notoptol

Notoptol is a natural product of Notopterygium, Apiaceae. The catalog number is TN6452 and the CAS number is 88206-49-9. Notoptol can be used as a reference standard.

Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one), a natural compound extracted from the umbelliferae plant Qiangwu, is a potent inhibitor of nitric oxide production, inhibiting LPS-induced NO production in RAW 264.7 cells with an IC50 value of 36.6 μM.

O-Methylnotoptol is a natural coumarin compound isolated from the dried rhizomes and roots of Notopterygium incisum.O-Methylnotoptol inhibits LPS-induced NO production in RAW 264.7 macrophages (IC₅₀ = 23.9 ± 2.9 μM).