nitrobenzylthioinosine

Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.

Nitrobenzylthioinosine 5'-monophosphate (NBMPR-P) is a nucleoside analogue and the prodrug form of the potent nucleoside transport inhibitor Nitro-benzylthioinosine (NBMPR). NBMPR-P effectively obstructs nucleoside transport in vivo and mitigates host toxicity in tumor-bearing mice subjected to high-dose tuberculin administration.

2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively)