nfκb control

SN50M (NF-κB Control) is a synthetic peptide containing a hydrophobic region and a mutant nuclear localization sequence that enters cells but does not inhibit NF-κB nuclear translocation or induce apoptosis.

gamma-Linolenic acid (Standard) is the standard substance of gamma-Linolenic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced reactive oxygen species generation including lipid peroxidation, cell growth inhibition, and heme oxygenase-1 production for antioxidant protection against oxidative stress. Further experiments have noted that γ-Linolenic acid inhibits inflammatory responses through inactivation of NFκB and activator protein-1 by suppressed oxidative stress.

Myristic acid (Standard) is the standard substance of Myristic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Myristic acid (Crodacid) , a 14 carbon saturated fatty acid, is a rare molecule in cells and is a substrate of some fatty acid desaturases. This compound has the ability to acylate proteins by covalently binding to the N-terminal glycine residues, in a process called N-terminal myristoylation. Myristoylation of substrate proteins by this fatty acid has the potential to activate and mediate many physiological pathways. Furthermore, saturated fatty acids have been reported to be essential for biological activities of lipopolysaccharides and have demonstrated the ability to induce expression of COX-2 and NFκB (nuclear factor κB) activation.

Triphenyl phosphate (Standard) is the standard substance of Triphenyl phosphate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Triphenyl phosphate can disrupt placental tryptophan metabolism by activating MAOA/ROS/NFκB, leading to abnormal neural behavior. It promotes oxidative stress by inducing inflammatory factors such as nuclear factor κ B (NFκB), interleukin-6, and tumor necrosis factor α. Additionally, triphenyl phosphate may cause allergic contact dermatitis.