netupitant

Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).

Netupitant D6 is the deuterium labeled Netupitant, which is a selective and orally active antagonist of neurokinin-1 receptor.

Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.

N-desmethyl Netupitant is a metabolite of Netupitant and a potential Substance-P receptor agonist. It can be used for researching cardiovascular diseases and neurological disorders.

Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.

Monohydroxy Netupitant D6 is a metabolite of Netupitant.

N-desmethyl Netupitant D6 is the deuterium labeled N-desmethyl Netupitant, which is a Netupitant metabolite.

Netupitant N-oxide D6 is a Netupitant metabolite, is the deuterium labeled Netupitant N-oxide.

Netupitant N-oxide (3)-d6 is a deuterated compound of Netupitant N-oxide (3). Netupitant N-oxide (3) has a CAS number of 910808-11-6.

Fosnetupitant is a methylene phosphate prodrug of Netupitant. It has a pKi of 9.5 for the human NK1 receptor.

Fosnetupitant chloride monohydrochloride (Pro-netupitant chloride monohydrochloride) is a selective NK1 antagonist exhibiting high affinity for the human NK1 receptor with a pK i value of 9.5, and a lower affinity for the NK3 receptor with a pK i of 6.1. It serves as a methylene phosphate prodrug of Netupitant [1].

6-(4-methylpiperazin-1-yl)-4-o-tolylnicotinamide can be used in the synthesis of befetupitant and netupitant.