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By Target- MLK
- NADPH-oxidase(1)
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Results for "
necrox-7
" in TargetMol Product Catalog- Inhibitors & Agonists2
NecroX-7
LC-280126, LC28-0126, LC28 0126
T99481120332-55-9
NecroX-7 (LC-280126) is a potent free radical scavenger and HMGB1 (high-mobility group box 1) inhibitor. It serves as an antidote to acetaminophen toxicity and exerts a protective effect by preventing HMGB1 release in ischemia reperfusion injury. Additionally, NecroX-7 inhibits HMGB1-induced release of TNF and IL-6 and the expression of TLR-4 and receptor for advanced glycation end products. This compound may be used for graft-versus-host disease (GVHD) research [1].
- $51
Size
QTY
NecroX-2
NecroX2
T2023751120333-38-1
NecroX-2 is a cell-permeable necrosis inhibitor with antioxidant properties. NecroX-2 selectively suppresses necrotic cell death triggered by oxidative stress. NecroX-2 does not confer protection against apoptosis induced by staurosporine or etoposide but shows protective effects under conditions such as cold shock, hypoxia, and oxidative stress in vitro.
- $195
Size
QTY
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