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(1)
By Target- MLK
- Necroptosis(1)
- RIP kinase(1)
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Results for "
necrosome
" in TargetMol Product Catalog- Inhibitors & Agonists2
Necrosulfonamide
(E)-Necrosulfonamide
T69041360614-48-7
Necrosulfonamide ((E)-Necrosulfonamide) is a necroptosis inhibitor that targets MLKL and is selective. Necrosulfonamide prevents the MLKL-RIP1-RIP3 necrosomal complex from interacting with its downstream effectors.
- $52
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QTY
RIP1-IN-1
T206258
RIP1-IN-1 is an orally bioavailable RIP1 inhibitor with a high binding affinity (Kd: 110 nM). This compound exhibits significant activity against necroptosis and effectively suppresses necrosome formation by inhibiting the phosphorylation of RIP1, RIP3, and MLKL pathways. RIP1-IN-1 can inhibit necroptosis and is applicable in research on acute liver injury.
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