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n-butyl analogue

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
  • Peptide Products
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    TargetMol | Peptide_Products
Macitentan (n-butyl analogue)
T11935556797-16-1
Macitentan n-butyl analogue, a derivative of Macitentan, functions as an orally active dual antagonist targeting both endothelin ETA and ETB receptors. This compound shows promise for treating idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH), leveraging its non-peptide structure for potential therapeutic applications.
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10-14 weeks
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Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH
T41066920519-32-0
Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide consisting of N-(9-fluorenylmethoxycarbonyl)-L-aspartic acid β-tert-butyl ester and a threonine analogue incorporating a non-native proline mimic with dimethyl substitution at the pseudopeptide bond.
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4-6 weeks
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