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Results for "
mrk-016
" in TargetMol Product Catalog- Inhibitors & Agonists1
MRK-016
MRK016
T12105342652-67-9
MRK-016 is a selective GABAA α5 receptor inverse agonist negative allosteric modulator, (IC50=3 nM) with the advantages of being orally available and penetrating the blood-brain barrier.MRK-016 increases long time period potentiation (LTP) in mouse hippocampal slices, with memory-improvement, antidepressant, and pain-treating effects.
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