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By Target- GABA Receptor
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Results for "
mrk 016
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- MRK-016MRK016T12105342652-67-9MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, (IC50=3 nM) with the advantages of being orally available and penetrating the blood-brain barrier.MRK-016 increases long time period potentiation (LTP) in mouse hippocampal slices, with memory-improvement, antidepressant, and pain-treating effects.
- $42
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