motilinreceptor

[Leu13]-Motilin (KW-5139) is an analogue of the gastrointestinal hormone motilin that induces concentration-dependent contractions in rabbit gastrointestinal tissues, including the gastric antrum, duodenum, jejunum, ileum, and descending colon in vitro [1].

Motilin (26-47), human and pig are endogenous Motilin receptor ligands in Chinese hamster ovarian cell lines, with Ki and EC50 at 2.3 nM and 0.3 nM, respectively.

Camicinal is a novel, highly potent, and selective motilin receptor agonist with a pEC₅₀ of 7.9.

MA-2029 is selective for the motilin receptor over various other receptors and ion channels. MA-2029 is a selective and competitive motilin receptor antagonist (IC50=4.9 nM). MA-2029 may be useful for gastrointestinal disorders associated with disturbed g

RWJ-68022 (Example 9) is a cyclopentene derivative that serves as a motilin receptor antagonist. It competes with motilin and erythromycin at motilin receptor sites and is applicable in research on gastrointestinal disorders.

KC-11458 is a motilin (motilin) agonist that enhances gastric emptying.

Idremcinal is a motilin receptor agonist.

Atilmotin is a gastrointestinal agent for treating motility disorders.

DS-3801b is a non-macrolide GPR38 agonist with an N-methylaniline structure for the study of functional gastrointestinal disorders.

Mitemcinal is a motilin agonist.

ANQ-11125 TFA is a potent, selective motilin antagonist, exhibiting a pKd of 8.24. It effectively inhibits motilide-induced contractions in rabbit models, as demonstrated in vitro [1] [2].

[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist [1][2].

Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.