motilinreceptor

[Leu13]-Motilin (KW-5139) is an analogue of the gastrointestinal hormone motilin that induces concentration-dependent contractions in rabbit gastrointestinal tissues, including the gastric antrum, duodenum, jejunum, ileum, and descending colon in vitro [1].

Motilin (26-47), human and pig are endogenous Motilin receptor ligands in Chinese hamster ovarian cell lines, with Ki and EC50 at 2.3 nM and 0.3 nM, respectively.

Atilmotin is a gastrointestinal agent for treating motility disorders.

ANQ-11125 TFA is a potent, selective motilin antagonist, exhibiting a pKd of 8.24. It effectively inhibits motilide-induced contractions in rabbit models, as demonstrated in vitro [1] [2].

[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist [1][2].

Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.