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Results for "
momelotinib mesylate
" in TargetMol Product Catalog- Inhibitors & Agonists1
Momelotinib Mesylate
CYT387 (Mesylate)
T150371056636-07-7
Momelotinib Mesylate is an ATP-competitive JAK1 JAK2 inhibitor (IC50: 11 nM 18 nM). It has 10-fold selectivity versus JAK3.
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T708231380317-28-1
Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.
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LM-1149, CYT387, CYT11387
T18491056634-68-4
Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells.
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CYT387 sulfate salt
T150381056636-06-6
Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.
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