modafinil

CRL-40940 is a selective dopaminergic reuptake inhibitor

(S)-CE-123 is an innovative and highly selective atypical dopamine transporter (DAT) inhibitor, exhibiting an EC 50 of 2.76 μM in uptake inhibition assays performed in HEK293 cells with stable expression of human DAT isoforms. As a Modafinil analogue, (S)-CE-123 can cross the blood–brain barrier and enhances cognitive and motivational functions in experimental animals [1] [2].

JJC8-088, a potent DAT inhibitor, is derived from Modafinil and serves as a novel ligand. This compound is utilized in research on psychostimulant use disorders [1].

JJC8-088 dioxalate, a dioxalate salt form of JJC8-088, is a derivative of modafinil. This compound acts as an inhibitor of the dopamine transporter (DAT). In rat models, JJC8-088 dioxalate exhibits behavioral characteristics similar to those of cocaine, making it useful for research into stimulant use disorders.