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mls0322825

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MLS-0322825
T212833853310-63-1
MLS-0322825 is a highly selective, orally active, low-molecular-weight protein tyrosine phosphatase (LMPTP/LMW-PTP) non-competitive inhibitor that exhibits potent inhibitory activity against the LMPTP-A subtype (IC₅₀ = 3.3 μM) and weaker inhibitory activity against the LMPTP-B subtype (IC₅₀ ≈ 40 μM). MLS-0322825 effectively increases IR phosphorylation levels in the liver and reduces blood glucose and insulin levels in obese mice. MLS-0322825 exhibits potential antitumor activity and can be used in tumor research.
  • $195
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