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(1)
By Target- Apoptosis
- Aurora Kinase(1)
- Autophagy(1)
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Results for "
mln8237
" in TargetMol Product Catalog- Inhibitors & Agonists1
Alisertib
MLN 8237
T22411028486-01-2
Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.
- $50
Size
QTY
T384281028486-06-7
Alisertib Sodium (MLN 8237 Sodium)is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis, and can also inhibit STAT3 Tyr705 phosphorylation, resulting in downregulation of c-Myc expression.
- $42
Size
QTY
T712321208255-63-3
Alisertib sodium hydrate is a salt of Alisertib --- an inhibitor of Aurora A kinase with potential antineoplastic activity. Alisertib binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
- $1,670
Size
QTY
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