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mln-4760

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
MLN-4760
T16116305335-31-3
MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
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(R)-MLN-4760
T72913305335-29-9
(R)-MLN-4760, the R-enantiomer of MLN-4760, functions as an ACE2 inhibitor with an IC50 of 8.4 μM, indicating it is the less active isomer.
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6-8 weeks
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