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Results for "
ml 228
" in TargetMol Product Catalog- Inhibitors & Agonists2
Pradefovir
ICN-2001-3, MB-6866, ICN-20013, MB-06866, Remofovir
T28449625095-60-5
Pradefovir (Remofovir) is a reverse transcriptase inhibitor potentially for treatment of chronic HBV infection. Pradefovir is also a liver-targeted prodrug of adefovir. After metabolic activation, Pradefovir was converted to PMEA (9-(2-phosphonylmethoxyethyl)adenine) in human liver microsomes with a K(m) of 60 microM, a maximum rate of metabolism of 228 pmol min mg protein, and an intrinsic clearance of about 359 ml min.
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