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mklp-2

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
MKLP2-IN-1
T2055382929345-46-8
MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.
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10-14 weeks
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Paprotrain
(alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile
T1235957046-73-8
Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
  • $40
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