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By Target- Epigenetic Reader Domain
- Histone Methyltransferase(1)
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By Target By ResearchField- Cancer(1)
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Results for "
mi3454
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- MI-3454T395842134169-43-8MI-3454 is an orally active, selective and potent inhibitor of Menin-MLL1 interaction that inhibits the proliferation and induces differentiation of acute leukemia cells with MLL1 translocation or NPM1 mutation.MI-3454 induces complete remission or regression of leukemia in a mouse model of leukemia with MLL1 rearrangement or NPM1 mutation through the down-regulation of key genes involved in leukemogenesis. complete remission or remission.
- $198
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