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By Target- Histone Methyltransferase
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Results for "
mi-3454
" in TargetMol Product Catalog- Inhibitors & Agonists1
MI-3454
T395842134169-43-8
MI-3454 is an orally active, selective and potent inhibitor of Menin-MLL1 interaction that inhibits the proliferation and induces differentiation of acute leukemia cells with MLL1 translocation or NPM1 mutation.MI-3454 induces complete remission or regression of leukemia in a mouse model of leukemia with MLL1 rearrangement or NPM1 mutation through the down-regulation of key genes involved in leukemogenesis. complete remission or remission.
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