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metallo-β-lactamase type 2

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
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    TargetMol | Recombinant_Protein
Metallo-β-lactamase-IN-6
T602391439899-44-1
Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. Additionally, Metallo-β-lactamase-IN-6 exhibits potent synergistic antibacterial properties when combined with Meropenem, particularly against engineered Escherichia coli strains and clinically isolated Pseudomonas aeruginosa carrying the VIM-2 MBL gene [1].
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6-8 weeks
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Metallo-β-lactamase-IN-7
T604942752453-58-8
Metallo-β-lactamase-IN-7 is a potent inhibitor of VIM-type metallo-β-lactamase with IC50 values of 0.019 μM, 13.64 μM, and 0.38 μM for VIM-2, VIM-1, and VIM-5, respectively. Metallo-β-lactamase-IN-7 also enhances the antibacterial activity of Meropenem against Gram-negative bacterial strains [1].
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6-8 weeks
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