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(2)
By Target- Apoptosis
- Epigenetic Reader Domain(2)
- Histone Methyltransferase(1)
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Results for "
meninmll inhibitor mi2
" in TargetMol Product Catalog- Inhibitors & Agonists2
Menin-MLL inhibitor MI-2
Cited
MI-2, MI2, MI 2, Menin-MLL inhibitor 2, Menin-MLL Inhibitor
T26491271738-62-5
Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
- $35
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CitedMenin-MLL inhibitor MI-2 dihydrochloride
T211697
Menin-MLL inhibitor MI-2 dihydrochloride is a competitive and selective inhibitor of the Menin-MLL interaction, with an IC50 value of 446 nM and a Ki value of 158 nM. It reduces the expression of target genes such as HOXA9 and MEIS1, inhibits the proliferation of leukemic cells, and induces apoptosis and differentiation. Menin-MLL inhibitor MI-2 dihydrochloride shows potential for research in MLL-rearranged acute leukemias, such as acute myeloid leukemia and acute lymphoblastic leukemia.
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