maprotiline

Maprotiline-D3 hydrochloride is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline hydrochloride (T0172) is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in rat brain and peripheral tissues. It reduces isolation-induced aggressive behavior and inhibits electrical foot-shock stimulation-induced belligerence in mice when administered at doses ranging from 3 to 10 mg/kg. Maprotiline also reduces aggressive behavior in rhesus monkeys housed in groups. Formulations containing maprotiline have been used in the treatment of depression and anxiety.

Maprotiline-D3 Hydrochloride (Standard) is a reference standard of Maprotiline-D3 Hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications. Maprotiline-d3 is used as an internal standard when conducting quantitative analysis of Maprotiline by gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry. Maprotiline is a tricyclic antidepressant.

Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

Maprotiline inhibits cell proliferation and metastasis with anticancer effects. Maprotiline induces apoptosis in cancer cells by targeting ERK signaling pathway and CRABP1. Maprotiline is a highly selective norepinephrine reuptake blocker with potent antidepressant properties. [1][2].

Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin.

Maprotiline-D5 hydrochloride is a deuterated compound of Maprotiline Hydrochloride. Maprotiline Hydrochloride (T0172) has a CAS number of 10347-81-6. Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

Maprotiline hydrochloride (Standard) is a reference standard for research and analysis in studies involving Maprotiline hydrochloride. Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

N-Desmethyl Maprotiline HCl (Standard) is a reference standard of N-Desmethyl Maprotiline HCl intended for quantitative analysis, quality control, and related biochemical research applications.

Tamitinol is a neurotropic drug. It has been found to help symptoms of obsessive rumination in conjunction with maprotiline.

Levoprotiline an antidepressant compound that is the R-(-) enantiomer of Oxaprotiline, acts comparably to Oxaprotiline and has a shorter latency to onset of action. It is the successor to the second-generation antidepressant maprotiline.