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By Target- Reactive Oxygen Species
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By Target By ResearchField- Cardiovascular System(1)
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Results for "
m6766
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Isotope Products1
- Reference Standards1
M6766
T212821696628-90-7
M6766 is a selective and potent inhibitor of endoplasmic reticulum oxidoreductase 1α (ERO1α), exhibiting an IC50 of 1.4 uM and a KD of 1.1 uM. It also inhibits ERO1β with an IC50 of 7.2 uM. M6766 exerts its inhibitory effect by binding to the flavin adenine dinucleotide (FAD)-binding pocket of ERO1α. Functionally, M6766 suppresses granule secretion, αIIbβ3 integrin activation, Ca2+ mobilization, and platelet aggregation. It serves as a significant chemical probe for investigating the molecular pathways of arterial thrombosis and neurological disorders, such as ischemic stroke.
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Delamanid D4 (Standard)
Delamanid-[D4] (Standard)
TMSM-67662747917-54-8
Delamanid D4 (Standard) is a reference standard of Delamanid D4 intended for quantitative analysis, quality control, and related biochemical research applications.
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