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(2)
By Target- FLT
- c-Met/HGFR(2)
- Discoidin Domain Receptor (DDR)(1)
- ROS(1)
- ROS Kinase(1)
- TAM Receptor(1)
- Tyrosine Kinases(1)
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Results for "
ly 2801653
" in TargetMol Product Catalog- Inhibitors & Agonists2
Merestinib
LY2801653
T34551206799-15-6
Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing the constitutively activated c-Met protein.
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Merestinib dihydrochloride
LY 2801653 dihydrochloride, LY2801653 dihydrochloride
T158081206801-37-7
Merestinib dihydrochloride (LY2801653 dihydrochloride) is an orally available kinase inhibitor with antitumor activity that inhibits MET, AXL, RON, and MKNK1 2, and inhibits the growth of NTRK fusion-carrying tumors.
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