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By Target- Apoptosis
- Autophagy(1)
- p38 MAPK(1)
- Others(1)
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Results for "
ly 2228820
" in TargetMol Product Catalog- Inhibitors & Agonists2
ralimetinib dimesylate
Cited
LY2228820 dimesylate
T6047862507-23-1
Ralimetinib dimesylate (LY2228820 dimesylate) is the dimesylate salt form of LY2228820, a tri-substituted imidazole derivative and orally available p38 mitogen-activated protein kinase (MAPK) inhibitor with potential anti-inflammatory and antineoplastic activities.
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CitedRalimetinib
LY2228820
T16721862505-00-8
Ralimetinib selectively inhibits phosphorylation of MK2 (Thr334) and has no effect on phosphorylation of p38α MAPK, JNK, ERK1 2, c-Jun, ATF2, or c-Myc. Ralimetinib is an effective and selective, ATP-competitive inhibitor of p38 MAPK α β (IC50s: 5.3 and 3.
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