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By Target- Proteasome
- Parasite(1)
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- Amylin Receptor
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- Apelin receptor
- Arrestin
- Bombesin Receptor
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- cAMP
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Results for "
lxe-408
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- LXE408LXE408T392141799330-15-6LXE408 is an orally active, kinetoplastid-selective proteasome inhibitor, exhibiting non-competitive inhibitory effects. It demonstrates an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. Moreover, LXE408 shows limited ability to traverse the blood-brain barrier. Hence, LXE408 holds promise for advancing research in the field of visceral leishmaniasis (VL).Inquiry
- LXE408 fumarateLXE408 fumarate (1799330-15-6 Free base)T39214LLXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. LXE408 fumarate has a low propensity to cross the blood brain barrier. LXE408 fumarate has the potential for visceral leishmaniasis (VL) research.
- $332
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