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Results for "

lumacaftor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
Lumacaftor
VX-809, VRT 826809
T2595936727-05-8
Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
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TargetMol | Citations Cited
NJH-2-057
T73827
NJH-2-057 is an EN523 OTUB1 recruiter linked to lumacaftor, a agent used to treat cystic fibrosis that binds ΔF508-CFTR .
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NJH-2-056
T74277
NJH-2-056 is a deubiquitinase-targeting chimera (DUBTAC) linking the OTUB1 recruiter EN523 to the CFTR chaperone lumacaftor. NJH-2-056 can be used for cystic fibrosis research [1] .
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CFTR corrector 13
T89629
CFTRcorrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector with an EC50 value of 3.14 μM. This compound enhances the function of CFTR channels, particularly when used in conjunction with Lumacaftor, leading to a dose-dependent increase in CFTR activity. CFTRcorrector 13 is utilized in research related to cystic fibrosis (CF) and other CFTR-associated diseases.
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