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(2)
By Target- CFTR
- Autophagy(1)
- PROTACs(1)
- Others(1)
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By Target By ResearchField- Chromosomal Disease(1)
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Results for "
lumacaftor
" in TargetMol Product Catalog.- Inhibitors & Agonists4
- PROTAC Products1
- LumacaftorVX-809, VRT 826809T2595936727-05-8Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
- $43
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Cited - CFTR corrector 13T89629CFTRcorrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector with an EC50 value of 3.14 μM. This compound enhances the function of CFTR channels, particularly when used in conjunction with Lumacaftor, leading to a dose-dependent increase in CFTR activity. CFTRcorrector 13 is utilized in research related to cystic fibrosis (CF) and other CFTR-associated diseases.
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