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(1)
By Target- Histamine Receptor
- Leukotriene Receptor(1)
- PAFR(1)
- Others(1)
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Results for "
ltd4 antagonist 1
" in TargetMol Product Catalog- Inhibitors & Agonists4
LTD4 antagonist 1
T10057136564-67-5
LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM).
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Rupatadine
UR-12592, UR12592
T36618158876-82-5
Rupatadine (UR-12592, rupatadine) is a potent and orally available dual antagonist of PAF and histamine H1 receptors with Ki values of 0.55 μM and 0.1 μM, respectively, which provides relief of allergic symptoms and anti-inflammatory properties, and is used in allergic rhinitis and chronic urticaria.
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LTD4 antagonist 2
T203302107813-86-5
LTD4 antagonist 2 (compound 6) functions as a leukotriene D4 (LTD4) antagonist with an IC50 of 2.8 μM for the cysteinyl leukotriene 1 receptor (CysLT1R). Additionally, it acts as an agonist for the G protein-coupled bile acid receptor 1 (GPBAR1), making it applicable for research into colitis, metabolic syndrome, and other GPBAR1- and CysLT1R-related diseases.
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Ritolukast
Wy-48252
T87336111974-60-8
Ritolukast (Wy-48252), an orally active aerosol leukotriene (LTD 4 E 4) receptor antagonist, effectively inhibits bronchoconstriction induced by aerosol LTD 4 in guinea pigs, demonstrating an ID 50 of 0.5mg kg [1].
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