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Results for "

losmapimod

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    2
    TargetMol | All_Pathways
  • Losmapimod
    SB856553, GW856553X, GW856553, GSK-AHAB
    T2277585543-15-3
    Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).
    • $30
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    TargetMol | Citations Cited
  • Losmapimod hydrochloride
    T2127251246654-84-1
    Losmapimod hydrochloride (GW856553X) is an orally active, potent, and highly selective p38 alpha/beta MAPK inhibitor (IC50 = 0.8 nM). It greatly reduces the release of pro-inflammatory cytokines, including TNF-alpha and IL-6, by blocking inflammatory signaling cascades, showing remarkable efficacy in COPD and severe cardiovascular inflammation models.
    • $195
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