lmptp-a

LMPTP INHIBITOR 1 hydrochloride is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM for LMPTP-A.

MDK-4823, also known as LMPTP inhibitor1, is a potent low-molecular-weight tyrosine phosphatase (LMPTP) inhibitor. LMPTP is highly expressed in insulin-target tissues. LMPTP promotes diabetes and insulin resistance in obesity.

LMPTP Inhibitor 1 Dihydrochloride is a compound selectively targeting low molecular weight protein tyrosine phosphatase (LMPTP), exhibiting potent inhibitory activity with an IC50 value of 0.8 μM for LMPTP-A.

MLS-0322825 is a highly selective, orally active, low-molecular-weight protein tyrosine phosphatase (LMPTP/LMW-PTP) non-competitive inhibitor that exhibits potent inhibitory activity against the LMPTP-A subtype (IC₅₀ = 3.3 μM) and weaker inhibitory activity against the LMPTP-B subtype (IC₅₀ ≈ 40 μM). MLS-0322825 effectively increases IR phosphorylation levels in the liver and reduces blood glucose and insulin levels in obese mice. MLS-0322825 exhibits potential antitumor activity and can be used in tumor research.