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By Target- PD-1/PD-L1
- Retinoid Receptor(1)
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Results for "
lg 100268
" in TargetMol Product Catalog- Inhibitors & Agonists1
LG100268
LGD1268, LGD 1268, LG268, LG-100268, ALRT 268
T19703153559-76-3
LG100268 is a potent, selective, and orally active retinoid X receptor (RXR) agonist that agonizes RXR-α, RXR-β, and RXR-γ at the nanomolar level, selectively exceeding the RAR by three orders of magnitude.LG100268 is capable of inducing transcriptional activation in adipocytes; affecting the RXRs and their chaperone receptor, Foxl2 Dmrt1, to induce flounder masculinization in juvenile flounder; inhibits keratin 17 expression in nigrostriatal epithelial cells; and increases PD-L1 expression in HER2 or triple-negative breast cancer.
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