lee011

Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and exhibits over 1,000-fold reduced potency against the cyclin B/CDK1 complex.

Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50:10/39 nM).

Ribociclib hydrochloride (LEE011 HCl) is a selective, orally active cyclin-dependent kinase CDK4/6 inhibitor (IC50=10/39 nM) that blocks cell cycle progression and inhibits tumor cell proliferation.

Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.

Ribociclib-D6 is a deuterated compound of Ribociclib (T6199) (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.

Ribociclib-D8 is the deuterated form of Ribociclib (T6199), also known as LEE011, which acts as a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM. Its activity against the cyclin B/CDK1 complex is over 1000 times weaker.

Ribociclib-D6 (Standard) is a reference standard of Ribociclib-D6 intended for quantitative analysis, quality control, and related biochemical research applications. Ribociclib-d6 (LEE011-d6) is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.