ketotifen

Ketotifen (HC 20-511) is a second-generation, orally active, noncompetitive histamine 1 (H1) receptor antagonist and mast cell stabilizer. It inhibits 6-phosphogluconate dehydrogenase (PGD) in vitro and exhibits antiviral activity against SARS-CoV-2 and the Influenza virus. Ketotifen is also used in research on autoimmune encephalomyelitis (EAE) and in the prevention of asthma attacks.

Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.

Ketotifen fumarate (Standard) is the standard substance of Ketotifen fumarate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.

Picumast dihydrochloride is a prophylactically active anti-allergic compound which combines inhibition of mediator release and action. The activity profile of PDH differs clearly from that of known prophylactic anti-allergic drugs such as DSCG and ketotifen.