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By Target- Akt
- DNA/RNA Synthesis(1)
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Results for "
kahalalide a
" in TargetMol Product Catalog.- Inhibitors & Agonists2
Kahalalide A
T25565179733-11-0
Kahalalide A has antimycobacterial activity isolated from the mollusk Elysia rufescens.
- $1,520
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Kahalalide F
T213972149204-42-2
Kahalalide F is a novel marine-derived antitumor agent known for inhibiting DNA synthesis. It exhibits cytotoxicity that is not correlated with the expression levels of the multidrug resistance gene MDR1 or the tyrosine kinase HER2/NEU, and is only slightly related to the expression of the anti-apoptotic protein BCL-2. Kahalalide F hinders the PI3K-Akt signaling pathway by depleting ErbB3. Its effects are rapidly activated with short pulse treatments. The compound primarily induces cell death through oncosis (cellular swelling) in tumor cells. Kahalalide F can be utilized in studies of prostate cancer, breast cancer, vulvar cancer, and non-small cell lung cancer.
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