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(1)
By Target- FGFR
- Histone Acetyltransferase(1)
- PROTACs(1)
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Results for "
jhh7
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products1
Roblitinib
Cited
FGF-401
T42351708971-55-4
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits FGFR4, leading to the inhibition of tumor cell proliferation in FGFR4-overexpressing cells. It is a receptor tyrosine kinase upregulated in certain tumor cells and involved in proliferation, differentiation, angiogenesis, and survival.
- $53
Size
QTY
CitedQC-182
T2091453032646-96-8
QC-182 is a potent p300/CBP PROTAC degrader. It reduces p300 protein levels in SK-HEP-1 cells with a DC50 of 93 nM. QC-182 effectively inhibits cell growth in SK-HEP-1 and JHH7 cell lines, with IC50 values of 0.733 μM and 0.477 μM, respectively. QC-182 is applicable for hepatocellular carcinoma (HCC) research.
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