isavuconazole

Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.

Isavuconazole-D4 is a deuterium labeled Isavuconazole. Isavuconazole (T2305) is a triazole prodrug with antifungal activity against yeasts, molds, and dimorphic fungi.

Isavuconazole-D4 (Standard) is a reference standard of Isavuconazole-D4 intended for quantitative analysis, quality control, and related biochemical research applications.

Isavuconazole (Standard) is a reference standard for research and analysis in studies involving Isavuconazole. Isavuconazole (RO-0094815)(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557 with MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.

Isavuconazole-[13C, D4] (Standard) is a reference standard of Isavuconazole-[13C, D4] intended for quantitative analysis, quality control, and related biochemical research applications.

Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), which catalyzes the demethylation of