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Results for "
ire1α kinase in 2
" in TargetMol Product Catalog- Inhibitors & Agonists2
IRE1α kinase-IN-2
IRE1α kinase-IN-2
T388411414938-21-8
IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM and impeding IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. It also effectively inhibits the splicing of XBP1 mRNA in wild-type cell lines.
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IRE1α kinase-IN-9
T790631338933-30-4
IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α with an average IC50 value of less than 0.1 μM, and it is suitable for research into diseases related to the unfolded protein response or regulated IRE1-dependent decay (RIDD) [1].
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