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  • IRE1
    (4)
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Results for "

ire1/xbp1s

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    4
    TargetMol | All_Pathways
  • IXA6
    T625681021106-40-0
    IXA6, a novel IRE1/XBP1s agonist with potential vasoprotective activity, activates IRE1-XBP1s signaling and XBP1s transcriptional response, making it useful for studying neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
    • $299
    In Stock
    Size
    QTY
  • IXA4
    T93491185329-96-7
    IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1. IXA4-stimulated IRE1 activation also enhanced pancreatic function.
    • $34
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • MKC8866
    T155941338934-59-0
    MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 μM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth.
    • $80
    In Stock
    Size
    QTY
  • IXA62
    T206732956783-34-9
    IXA62 is an orally active, selective IRE1/XBP1s agonist (EC50= 0.31 μM) that can reduce Aβ secretion.
    • Inquiry Price
    10-14 weeks
    Size
    QTY