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int747

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Obeticholic Acid
INT-747, 6-Ethylchenodeoxycholic acid, 6-ECDCA
T1789459789-99-2
Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist with an EC50 of 99 nM and is able to upregulate IκB-α, KLF-2, and KLF-4 expression. Obeticholic Acid (6-ECDCA, INT-747) also shows potential for treating hepatic steatosis, inflammation, and fibrosis while increasing insulin sensitivity.
  • $41
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Obeticholic Acid-[D4] (Standard)
TMSM-3914
Obeticholic Acid-[D4] (Standard) is a reference standard of Obeticholic Acid-[D4] intended for quantitative analysis, quality control, and related biochemical research applications.
  • $533
4-6 weeks
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Obeticholic acid-d5
TMID-09141992000-80-2
Obeticholic acid-d5 is the deuterated form of Obeticholic acid. Obeticholic acid (INT-747) acts as a potent, selective, and orally active FXR agonist with an EC50 of 99 nM, exhibiting both anticholeretic and anti-inflammatory properties. Additionally, Obeticholic acid can induce autophagy (autophagy).
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Obeticholic Acid-d4
TMID-0511
Obeticholic Acid-d4 is the deuterated form of Obeticholic acid. Obeticholic acid (INT-747) acts as a potent, selective, and orally active FXR agonist, with an EC50 of 99 nM, exhibiting both anticholestatic and anti-inflammatory properties. Additionally, Obeticholic acid can induce autophagy (autophagy).
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