insecticidal

Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis.

L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.

Insecticidal agent 364 is a selective small molecule inhibitor of rapamycin kinase target protein. Insecticidal agent 364 has antitumor activity, and by inhibiting mTOR, Insecticidal agent 364 aims to disrupt signaling pathways involved in cancer cell growth and survival, thereby potentially inhibiting tumor growth.

Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg mL respectively.

Insecticidal agent 18 (compound 34) is an effective insecticide. It exhibits acaricidal activity.

Insecticidal agent 17 (compound 31) is a pesticide with an LC50 value of 0.759 mg mL against the diamondback moth.

Insecticidal agent 19 (Compound 7b) exhibits antimalarial activity by inhibiting dihydrofolate reductase-thymidylate synthase (DHFR-TS) and pteridine reductase 1 (PTR1) through the folate metabolic pathway. This compound also inhibits the promastigote and amastigote forms of Leishmania major, with IC50 values of 1.43 μM and 3.78 μM, respectively.

Insecticidal agent 20 (Compound 17) is an insecticide that binds to AChBP. It demonstrates effective insecticidal activity against mosquito larvae (LC50: 1.57 ppm) and pupae (LC50: 4.17 ppm).

Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].

Compound IA-8, an aryl isoxazoline derivative, exhibits insecticidal efficacy against M. separate [1].

α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.

Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S. frugiperda RyRs. It demonstrates outstanding insecticidal efficacy against lepidopteran pests and has applications in pest and disease research [1].

Insecticidal Agent 3, a multichitinase inhibitor and part of the insect growth regulators (IGRs) group, exhibits strong inhibition with Ki values of 0.8 μM, 11.9 μM, and 2.3 μM against Of ChtI, Of ChtII, and Of Chi-h enzymes, respectively. It demonstrates effective insecticidal activity against two lepidopteran pests by disrupting insect growth and molting processes [1].

Insecticidal agent 1 exhibits greater insecticidal potency than both obacunone and toosendanin.

Insecticidal Agent 7 (Compound 21m) is an insecticide that acts on insect ryanodine receptors (RyRs), exhibiting a potency with a LC 50 of 0.0937 mg L against Plutella xylostella. It demonstrates significant selectivity and minimal toxicity toward non-target organisms [1].

Epsilon-momfluorothrin (Momfluorothrin, (Z,1R,3R)-), a type I synthetic pyrethroid insecticide, exerts its insecticidal properties and triggers activation of the constitutive androstane receptor (CAR). Notably, its administration in rats has been observed to induce the development of hepatocellular tumors.

DRF-1042, an orally active camptothecin analog, exhibits anticancer and insecticidal activities by inhibiting DNA topoisomerase I. It has been studied for its efficacy against solid tumors, including prostate and colon cancers.

CRK12-IN-1 is a potent CRK12 inhibitor with insecticidal activity and exhibits inhibitory effects on Trypanosoma brucei (T.b. brucei) and Trypanosoma congolense (T. congolense) with EC50s of 1.3 and 18 nM, respectively, rapidly killing the pathogenic cells.

7-Methoxy-1-tetralone may have insecticidal activity.

Spirodiclofen (BAJ-2740) is a selective, non-systemic acaricide from the new chemical class of tetronic acid derivatives,with no cross resistance to currently available acaricides and with additional insecticidal properties.

Cottonseed oil, a cooking oil extracted from the seeds of cotton plants, has been considered the most insecticidal of vegetable oils.

Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.