infectious — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15017	CU-T12-9		TLR
	CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat...		TLR
T1237	Azathioprine	BW 57-322	Apoptosis , GPR , Rho
	Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.		Apoptosis , GPR , Rho
T7222	GS-441524	GS 441524 triphosphate	Others , SARS-CoV , DNA/RNA Synthesis
	GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.		Others , SARS-CoV , DNA/RNA Synthesis
T8360	(-)-β-pinene	(-)-β-Pinene,Nopinene	Antibacterial
	(-)-β-pinene (Nopinene) is inhibit infectious bronchitis virus (IBV) with an IC50 of 1.32 mM,with antimicrobial activity		Antibacterial
T9567	Samatasvir	ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719	HCV Protease
	Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.		HCV Protease
T40019	Thalidomide-5-NH2-CH2-COOH		Others
	Thalidomide-5-NH2-CH2-COOH (compound 114) is a selective inhibitor of the protomyosin receptor kinase. It is a ligand for E3 ligase and has potential for studying one or more diseases.		Others
T4990	Cefcapene pivoxil hydrochloride hydrate	Cefcapene Pivoxil Hydrochloride	Antibacterial , Antibiotic
	Cefcapene pivoxil hydrochloride hydrate is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity. After oral administration of cefcapene pivoxil, the es...		Antibacterial , Antibiotic
T26804	Biclotymol		Others
	Biclotymol is used in the study about infectious oropharyngeal diseases.		Others
T16465	Penicillin G benzathine	Benzathine benzylpenicillin,Benzathine penicilline G	Antibacterial
	Penicillin G benzathine has anti-bacterial infectious activity and can be used to study early syphilis.		Antibacterial
T8686	VUN65671		Others
	Compounds 35 are superior inhibitors of Ebola (Mayinga) and Marburg (Angola) infectious viruses.		Others
TN1145	Isofebrifugine		Parasite
	Isofebrifugine is an alkaloid from the plant Changshan of the Saxifrage family with antimalarial and anti-infectious activity.		Parasite
T72910	APOBEC3G-IN-1		Others
	APOBEC3G-IN-1 (MN136.0185) is a targeted APOBEC3G inhibitor with anti-HIV activity for the study of infectious diseases and cancer.		Others
T9218	Andrograpanin	19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE	p38 MAPK
	Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.		p38 MAPK
T78748	MtUng-IN-1		Antibacterial
	MtUng-IN-1 (Compound 18a) inhibits mycobacterial uracil DNA glycosylase (MtUng) with an IC50 value of 300 μM. MtUng-IN-1 is suitable for use in cancer and infectious disease research.		Antibacterial
T14044	4E2RCat		PERK
	4E2RCat is an eIF4E-eIF4G interaction inhibitor (IC50: 13.5 μM).		PERK
T11815	Lanopepden	GSK 1322322,GSK-1322322B,GSK-1322322J	Antibiotic
	Lanopepden (GSK 1322322) is a potent peptide deformylase inhibitor of Staphylococcus aureus, inhibiting ATCC 29213 and ATCC 25923 strains, and can be used in the study of pneumonia, dermatological and infectious diseases...		Antibiotic
T3028	Tripterin	Celastrol,Tripterine	Apoptosis , Mitophagy , Proteasome , Autophagy
	Tripterin (Celastrol) is a natural product, a proteasome inhibitor that inhibits the pancreatic rennet-like activity of the 20S proteasome (IC50=2.5 μM). Tripterin has anti-inflammatory, anti-infectious, and immunomodula...		Apoptosis , Mitophagy , Proteasome , Autophagy
T76687	Ibalizumab	TNX-355,TMB-355	HIV Protease
	Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4 receptor.Ibalizumab has anti-HIV-1 infectious activity and m...		HIV Protease
T6229	Daclatasvir	Daklinza,EBP 883,BMS-790052	HCV Protease
	Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.		HCV Protease
T76251L	Ac-FEID-CMK TFA		Pyroptosis
	Ac-FEID-CMK TFA is a selective zebrafish GSDMEb-derived peptide inhibitor that reduces mortality and renal injury in infectious shock.Ac-FEID-CMK TFA inhibits pyroptosis in vivo, attenuates septic AKI (acute kidney injur...		Pyroptosis