immunoadjuvant

Sodium lauryl sulfoacetate (Sodium houttuyfonate) is anti-pseudomonas agents, inhibits virulence-related motility of Pseudomonas.

AYK004 is an adenosine derivative that functions as a TLR7 8 agonist, enhancing immune responses by activating the TLR signaling pathway. It boasts an optimal hydrophilic-lipophilic balance, improving its loading rate and stability within immunoadjuvant systems like liposomes, and reduces the side effects of these systems during systemic immunization.

Mannitan oleate is a lipid produced through the chemical reaction between mannitane (the anhydride of mannitol) and oleic acid. It serves as an emulsifier, surfactant, and immunoadjuvant in vaccine formulation.

8-Mercaptoguanosine acts as an immunoadjuvant influencing the in vivo antibody response to the T-cell-independent antigen TNP-Ficoll. It boosts IgG1, IgG2, and IgG3 antibody responses without affecting IgM responses. Additionally, it enhances responses to weak antigens like pneumococcal polysaccharide and restores reactions in immunodeficient xid mice unresponsive to TNP-Ficoll.

Complete Freund's adjuvant (CFA) is an immunologic adjuvant emulsified with antigens, composed of heat-killed, inactivated Mycobacterium tuberculosis in a water-in-oil emulsion with paraffin oil. As a TLR ligand, it enhances the immune response to antigens in animals, induces Th1-type immune responses, and is commonly used to establish experimental models such as rheumatoid arthritis, persistent inflammatory pain, and experimental autoimmune myocarditis (EAM) in rats.