ic 83

Rabusertib (IC-83) is an inhibitor of the cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiating activity. Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non-Small Cell Lung Cancer.

Fosfomycin is an antibiotic that is produced by Streptomyces fradiae.

A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC 50 s of 12 nM, 45 nM and 7.5 nM against the ALK5, ALK4 and ALK7 induced transcription, respectively [1].

7-O-Methylrutin is a natural product exhibiting inhibitory activity against aldose reductase 1 (IC₅₀=21 µM).

STAT6-IN-11 is a STAT6 inhibitor with an EC₅₀ of 6 nM. It inhibits the secretion of CCL17 in human peripheral whole blood with an IC₅₀ of 83 nM through the IL-13–IL-13 receptor/IL-4 receptor pathway and can be used in research on skin diseases and respiratory diseases.