ibuprofend3

Ibuprofen-D3 is a deuterium labeled Ibuprofen. Ibuprofen (T1394) is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).

(S)-(+)-Ibuprofen-D3 is a deuterium labeled  (S)- (+)-Ibuprofen (T0448). (S)- (+)-Ibuprofen is the S (+)-enantiomer of Ibuprofen ,it is an inhibitor of COX-1 and COX-2 activity (IC50s of 2.1 μM and 1.6 μM).

Ibuprofen-D3 sodium is the deuterated form of Ibuprofen sodium, a COX-1 selective inhibitor with oral activity, exhibiting an IC50 value of 13 μM. It impedes cell proliferation, inhibits angiogenesis, and induces apoptosis. As a nonsteroidal anti-inflammatory agent and nitric oxide (NO) donor, Ibuprofen sodium (T60292) is utilized in research on pain, swelling, inflammation, infections, immunology, and cancer.

(R)-(-)-Ibuprofen-D3 is the deuterated form of  (R)- (-)-Ibuprofen (T17309). This isomer of Ibuprofen, while inactive against COX, is capable of inhibiting NF-κB activation. It possesses anti-inflammatory properties and can be used in studies focused on pain relief.

Ibuprofen-D3 (Standard) is a reference standard of Ibuprofen-D3 intended for quantitative analysis, quality control, and related biochemical research applications.