ibuprofen d3

(S)-(+)-Ibuprofen D3 is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen ,it is an inhibitor of COX-1 and COX-2 activity (IC50s of 2.1 μM and 1.6 μM).

Ibuprofen D3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).

Ibuprofen-d3 ((±)-Ibuprofen-d3) sodium is the deuterated form of Ibuprofen sodium, a COX-1 selective inhibitor with oral activity, exhibiting an IC50 value of 13 μM. It impedes cell proliferation, inhibits angiogenesis, and induces apoptosis. As a nonsteroidal anti-inflammatory agent and nitric oxide (NO) donor, Ibuprofen sodium is utilized in research on pain, swelling, inflammation, infections, immunology, and cancer.

(R)-(-)-Ibuprofen-d3 is the deuterated form of (R)-(-)-Ibuprofen. This isomer of Ibuprofen, while inactive against COX, is capable of inhibiting NF-κB activation. It possesses anti-inflammatory properties and can be used in studies focused on pain relief.

Ibuprofen-13C,d3 is a carbon-13 and deuterium-labeled form of Ibuprofen. It acts as an inhibitor of COX-1 and COX-2 with IC50 values of 13 μM and 370 μM, respectively, and possesses anti-inflammatory properties.