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human naaa

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
ARN 077
URB913
T103701373625-34-3In house
ARN 077 is a selective N-acylethanolamine acid amidase (NAAA) inhibitor (IC50: 7 nM for human NAAA). ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS.
    8-10weeks
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    ARN19702
    T95281971937-18-4
    ARN19702 is a selective, orally active, reversible, and brain-penetrant N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 230 nM for human NAAA, exhibiting a broad analgesic profile [1] [2].
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    10-14 weeks
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    TargetMol | Citations Cited
    ARN19689
    T398592320521-34-2
    ARN19689 is an effective inhibitor of human NAAA, demonstrating high potency in the low nanomolar range (IC 50 = 0.042 μM). The compound acts through a non-covalent mechanism, highlighting its ability to interact with the enzyme for inhibition.
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