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(1)
By Target- ATPase
- Apoptosis(1)
- Autophagy(1)
- Histone Methyltransferase(1)
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Results for "
hoxa9 expression
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Natural Products1
Neriifolin
NSC 123976, NSC123976, 17beta-Neriifolin, 17β-Neriifolin
T124830466-07-9
Neriifolin (17β-Neriifolin), a cardiac glycoside extracted from the unripe fruit of Cerbera manghas, is a Na+K+-ATPase inhibitor with anticancer activity that inhibits cell proliferation by suppressing HOXA9-dependent gene expression and inducing apoptosis in the human acute myeloid cell line, THP-1. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells and can be used in prostate cancer research.
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MI-2-2
MI22, MI 2 2
T280361454920-20-7
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
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